What pH does Panthenol work at?

Panthenol is most effective at a pH of 5.0–7.0.

What pairs well with Panthenol?

Panthenol pairs well with: ceramides, hyaluronic acid, centella.

Is Panthenol safe during pregnancy?

Panthenol is generally considered safe during pregnancy. Always confirm with your obstetrician.

The guides · Humectants

Panthenol

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Provitamin B5 — converts in skin to pantothenic acid. Humectant and soothing agent. Supports skin comfort during the introduction of actives (retinoids, acids). Associated with reduced TEWL.

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What it does

Provitamin B5 — converts in skin to pantothenic acid. Humectant and soothing agent. Supports skin comfort during the introduction of actives (retinoids, acids). Associated with reduced TEWL.

The facts

Effective pH: 5.0–7.0
Category: Humectants
Also known as: Vitamin B5, Provitamin B5, D-panthenol
Pregnancy: Generally considered fine; ask your doctor

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Pairs with · fights with

Pairs well with

Conflicts

None listed.

Before you use it

Consistently safe and well-tolerated across CIR assessments. Excellent as a bridge ingredient alongside potentially irritating actives.

On the label

Listed as "panthenol" or "d-panthenol". Often paired with allantoin and centella in soothing formulas. Effective at 1–5%; cosmetically elegant in serums and creams alike.

This guide is editorial, not medical advice. For a condition, a reaction or a medical question, see a dermatologist.