What pH does Peptides work at?

Peptides is most effective at a pH of 5.0–7.0.

What pairs well with Peptides?

Peptides pairs well with: hyaluronic acid, niacinamide, ceramides.

Is Peptides safe during pregnancy?

Peptides is generally considered safe during pregnancy. Always confirm with your obstetrician.

What should I not mix with Peptides?

Use with caution alongside: AHAs/BHAs at very low pH (may denature peptide chains); copper peptides + vitamin c (oxidation of copper).

The guides · Fine lines

Peptides

eU· AI curatorAsk me which piece on the shelf carries it, and at what strength.

Short amino acid chains that act as signalling molecules in skin. Signalling peptides (e.g.

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What it does

Matrixyl/palmitoyl tripeptide-1) communicate with fibroblasts; carrier peptides (e.g. copper peptide GHK-Cu) deliver trace minerals. May support the look of firmer, more resilient skin over time.

The facts

Effective pH: 5.0–7.0
Category: Fine lines
Also known as: Peptide, Matrixyl, Palmitoyl, Copper Peptide, Ghk-cu
Pregnancy: Generally considered fine; ask your doctor

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Pairs with · fights with

Pairs well with

Conflicts

AHAs/BHAs at very low pHmay denature peptide chains
Copper peptides + vitamin coxidation of copper

Before you use it

Apply after actives, before occlusive moisturizer (peptides need to reach receptors, not sit under an occlusive). Effects are gradual — 8-12 week commitment for visible change.

On the label

Look for named peptides: "palmitoyl tripeptide-1", "palmitoyl tetrapeptide-7" (Matrixyl 3000), or "copper tripeptide-1" (GHK-Cu). A vague "peptide complex" without named actives may be underdosed.

This guide is editorial, not medical advice. For a condition, a reaction or a medical question, see a dermatologist.